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.Three cases of Duchenne muscular dystrophy in Omani children.

To report three cases of Duchenne muscular dystrophy in Omani children. A retrospective study was carried out on three patients diagnosed as Duchenne muscular dystrophy based on the history of progressive muscle weakness and elevated serum creatine kinase, and on muscle biopsy findings showing progressive loss of muscle fibres. Muscular dystrophy was confirmed by family history, ultrasonography or muscle MRI. All three patients presented with proximal muscle weakness, with two having a history of scoliosis. All three patients had either raised or borderline serum creatine kinase values and three patients were asymptomatic. All three patients were of Arabian ethnic origin. The three patients in this report are the first from the Arabian peninsula with Duchenne muscular dystrophy to be diagnosed. Three cases of Duchenne muscular dystrophy were diagnosed in Omani children. These cases were confirmed by muscle biopsy and family history. This rare disease should be considered in the differential diagnosis of children who have unexplained muscular weakness, especially in those with a history of scoliosis.The preliminary results of a multicenter, randomized, double-blind, placebo-controlled trial to evaluate the efficacy of low-dose corticosteroids in early acute asthma attack in children.

Randomized, double-blind, placebo-controlled, clinical trial to evaluate the efficacy of low-dose corticosteroids in early acute asthma attack in children. Emergency departments and pediatric emergency units at six university hospitals in China. A total of 154 children with asthma attack in the Emergency Department (ED) of any of six participating sites within 24 hours of symptom onset were enrolled. Each patient received either oral prednisone (1.0 mg/kg) or placebo 2 hours after onset. 0b46394aab

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